Numbers, ROI and projections run today’s businesses. Change is something we would like to master, especially when it is expected to happen in an organization. It would be helpful to have equations and be able to predict the speed, velocity, and acceleration of a transformation and to extrapolate the challenges. But is it possible? And how can mathematics help with disruption and uncertainty, the driving forces behind modern change? Cecile Demailly challenges us to consider the potential that mathematics has for thinking and executing change at scale. 2+2 is not always 4.